Assessment of thrombocytopenia, sleep apnea, and cardiac involvement in GNE myopathy patients

• Published in: Muscle & nerve Vol. 65; no. 3; pp. 284 - 290
• Main Authors: Mori‐Yoshimura, Madoka, Kimura, Ayano, Tsuru, Ayumi, Yajima, Hiroyuki, Segawa, Kazuhiko, Mizuno, Katsuhiro, Oya, Yasushi, Noguchi, Satoru, Nishino, Ichizo, Takahashi, Yuji
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.03.2022; Wiley Subscription Services, Inc
• Subjects: Abnormalities; Apnea; Biomarkers; cardiac complication; Cardiomyopathy; Complications; Continuous positive airway pressure; Coronary artery disease; Distal Myopathies; Echocardiography; EKG; Electrocardiography; Epimerase; GNE myopathy; Heart diseases; Humans; IgG antibody; Immunoglobulin G; Multienzyme Complexes; Muscular Diseases - diagnosis; Myopathy; N-Acetylglucosamine; Platelets; platelet‐associated IgG; Sleep; Sleep apnea; sleep apnea syndrome; Sleep Apnea Syndromes - diagnosis; Sleep disorders; Thrombocytopenia; platelet-associated IgG; GNE myopathy; cardiac complication; thrombocytopenia; sleep apnea syndrome

Introduction We previously identified UDP‐N‐acetylglucosamine 2‐epimerase (GNE) myopathy patients with sleep apnea and a past history of thrombocytopenia, but without disease‐specific cardiac involvement. This study aimed to clarify the occurrence, severity, and serial changes of these complications...