Circular RNA circ‐Foxo3 inhibits esophageal squamous cell cancer progression via the miR‐23a/PTEN axis

• Published in: Journal of cellular biochemistry Vol. 121; no. 3; pp. 2595 - 2605
• Main Authors: Xing, Yao, Zha, Wen‐Juan, Li, Xiao‐Min, Li, Hao, Gao, Fei, Ye, Ting, Du, Wang‐Qi, Liu, Yang‐Chen
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.03.2020
• Subjects: Cancer; Cell migration; Circular RNA; circ‐Foxo3; esophageal squamous cell cancer; Esophagus; FOXO3 protein; MicroRNAs; miRNA; miR‐23a; PTEN; PTEN protein; Ribonucleic acid; RNA; PTEN; esophageal squamous cell cancer; circ-Foxo3; miR-23a

Circ‐Foxo3 is a circRNA encoded by the human FOXO3 gene and works as a sponge for potential microRNAs (miRNAs) to regulate cancer progression. However, the role of circ‐Foxo3 in esophageal squamous cell cancer (ESCC) is not clear. In this study, circ‐Foxo3 was lowly expressed in cell lines and ESCC...