Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Positive Modulator of HGF/MET, Fosgonimeton, in Healthy Volunteers and Subjects with Alzheimer’s Disease: Randomized, Placebo-Controlled, Double-Blind, Phase I Clinical Trial - Hua, Xue; Church, Kevin; Walker, William; L’Hostis, Philippe; Viardot, Geoffrey; Danjou, Philippe; Hendrix, Suzanne; Moebius, Hans J. (Journal of Alzheimer's disease, 2022)
Keywords: Aged; Alzheimer Disease - drug therapy; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Healthy Volunteers; Hepatocyte Growth Factor - therapeutic use; Humans; Male; electroencephalography; Alzheimer’s disease; neurotrophic factor; hepatocyte growth factor; P300 component; ATH-1017; dementia; fosgonimeton; event-related potentials; ATH-1001