Top-Down versus Bottom-Up Approach in Children Presenting with Urinary Tract Infection: Comparative Effectiveness Analysis Using RIVUR and CUTIE Data

• Published in: The Journal of urology Vol. 206; no. 5; pp. 1284 - 1290
• Main Authors: Scott Wang, Hsin-Hsiao, Cahill, Dylan, Panagides, John, Logvinenko, Tanya, Nelson, Caleb
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Wolters Kluwer 01.11.2021
• Subjects: Child; Child, Preschool; Computer Simulation; Cystography - adverse effects; Cystography - methods; Female; Follow-Up Studies; Humans; Infant; Kidney - diagnostic imaging; Male; Models, Statistical; Radionuclide Imaging - adverse effects; Radionuclide Imaging - methods; Radiopharmaceuticals - administration & dosage; Recurrence; Technetium Tc 99m Dimercaptosuccinic Acid - administration & dosage; Ultrasonography; Urinary Bladder - diagnostic imaging; Urinary Tract Infections - diagnosis; Urinary Tract Infections - therapy; Urination; vesico-ureteral reflux; technetium Tc 99m dimercaptosuccinic acid; cystography; urinary tract infections

Purpose:The initial imaging approach to children with urinary tract infection (UTI) is controversial. Along with renal/bladder ultrasound, some advocate voiding cystourethrogram (VCUG), ie a bottom-up approach, while others advocate dimercaptosuccinic acid (DMSA) scan, ie a top-down approach. Compar...