A Study Examining Intravenous Ethanol-Conditioned Place Preference in C57BL/6J Mice

• Published in: Alcoholism, clinical and experimental research Vol. 21; no. 9; pp. 1661 - 1666
• Main Authors: Kelley, Brian M., Bandy, Angela-Leigh E., Middaugh, Lawrence D.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.12.1997; Lippincott Williams & Wilkins
• Subjects: Alcohol; Alcoholism and acute alcohol poisoning; Animals; Behavior, Animal - drug effects; Biological and medical sciences; C57BL/6J Mice; Conditioned Place Preference; Conditioning, Classical - drug effects; Conditioning, Operant - drug effects; Discrimination Learning - drug effects; Drug Discrimination; Ethanol - administration & dosage; Ethanol - pharmacology; Infusions, Intravenous; Injections, Intraperitoneal; Intravenous Ethanol; Medical sciences; Mice; Mice, Inbred C57BL; Reward; Self Administration; Toxicology; Vertebrata; Intraperitoneal administration; Mammalia; Intravenous administration; Ethanol; Conditioned place preference; Mouse; Animal; Rodentia; Reinforcement; Instrumental conditioning; Route of administration

The reinforcing effects of intravenous (IV) ethanol were examined in C57BL/6J (C57) mice with a conditioned‐place‐preference (CPP) paradigm. Before CPP testing, adult mice underwent jugular catheterization. On the following day, subjects were acclimated to a two‐compartment CPP chamber. A 15‐min non...