The DUF1996 and WSC domain‐containing protein Wsc1I acts as a novel sensor of multiple stress cues in Beauveria bassiana

• Published in: Cellular microbiology Vol. 21; no. 12; pp. e13100 - n/a
• Main Authors: Tong, Sen‐Miao, Wang, Ding‐Yi, Gao, Ben‐Jie, Ying, Sheng‐Hua, Feng, Ming‐Guang
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.12.2019
• Subjects: Beauveria bassiana; Cations; cell injury/sublethal injury; Cell membranes; Cell walls; Clonal deletion; Complementation; Conidia; Copper; Deletion mutant; filamentous fungi; Fungi; genotyping; Hog1 protein; Homology; Insects; Iron; Irradiation; Kinases; Magnesium; Metal ions; molecular genetic; Organic chemistry; Oxidants; Oxidizing agents; Phosphorylation; Protein kinase; Proteins; Signal transduction; stress response; Ultraviolet radiation; Vacuoles; Virulence; Zinc; cell injury/sublethal injury; filamentous fungi; stress response; molecular genetic; genotyping

Wsc1I homologues featuring both an N‐terminal DUF1996 (domain of unknown function 1996) and a C‐terminal WSC (cell wall stress‐responsive component) domain exist in filamentous fungi but have never been functionally characterized. Here, Wsc1I is shown to localize in the vacuoles and cell wall/membra...