Endogenous glucagon‐like peptide‐1 system response is impaired during ST‐elevation myocardial infarction in type 2 diabetes patients

• Published in: Diabetes, obesity & metabolism Vol. 21; no. 1; pp. 194 - 198
• Main Authors: Elbaz‐Greener, Gabby, Bloch, Olga, Kumets, Ilya, Blatt, Alex, Rapoport, Micha J.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.01.2019; Wiley Subscription Services, Inc
• Subjects: Adult; Aged; Aged, 80 and over; Angina; Angina pectoris; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - epidemiology; Dipeptidyl Peptidase 4 - metabolism; Dipeptidyl-peptidase IV; endogenous GLP‐1 system; Female; Glucagon; Glucagon-Like Peptide 1 - blood; Glucagon-Like Peptide 1 - metabolism; Heart attacks; Humans; Ischemia; Male; Middle Aged; Myocardial infarction; Peptidase; Peptides; Plasma levels; soluble DPP4; ST Elevation Myocardial Infarction - complications; ST Elevation Myocardial Infarction - epidemiology; ST Elevation Myocardial Infarction - metabolism; ST‐elevation myocardial infarction; type 2 diabetes; endogenous GLP-1 system; ST-elevation myocardial infarction; soluble DPP4; type 2 diabetes
• ISSN: 1462-8902; 1463-1326; 1463-1326
• DOI: 10.1111/dom.13490

We previously demonstrated increased glucagon‐like peptide‐1 (GLP‐1) secretion during acute ST elevation myocardial infarction (STEMI) in non‐diabetic (ND) patients. Whether the endogenous GLP‐1 system response is different in patients with type 2 diabetes (T2D) during STEMI is unknown. Patients wit...