Insights from the Biorepository and Integrative Genomics pediatric resource

• Published in: Nature communications Vol. 16; no. 1; pp. 4750 - 12
• Main Authors: Buonaiuto, Silvia, Marsico, Franco, Mohammed, Akram, Chinthala, Lokesh K., Amos-Abanyie, Ernestine K., Prins, Pjotr, Mozhui, Khyobeni, Rooney, Robert J., Williams, Robert W., Davis, Robert L., Finkel, Terri H., Brown, Chester W., Colonna, Vincenza
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 22.05.2025; Nature Publishing Group; Nature Portfolio
• Subjects: 631/208/457; 692/308/2056; Adolescent; Asthma - epidemiology; Asthma - genetics; Biological Specimen Banks; Child; Cohort Studies; Environmental factors; Female; Genetic diversity; Genetic variance; Genetic Variation; Genomic analysis; Genomics; Genomics - methods; Humanities and Social Sciences; Humans; Male; Minority & ethnic groups; multidisciplinary; Pediatrics; Precision medicine; Race; Racial Groups - genetics; Science; Science (multidisciplinary); Tennessee - epidemiology; Urban areas; Tennessee

The Biorepository and Integrative Genomics (BIG) Initiative in Tennessee has developed a pioneering resource to address gaps in genomic research by linking genomic, phenotypic, and environmental data from a diverse Mid-South population, including underrepresented groups. We analyzed 13,152 exomes fr...