Comparison of strength testing modalities in dysferlinopathy

• Published in: Muscle & nerve Vol. 66; no. 2; pp. 159 - 166
• Main Authors: Reash, Natalie F., James, Meredith K., Alfano, Lindsay N., Mayhew, Anna G., Jacobs, Marni, Iammarino, Megan A., Holsten, Scott, Sakamoto, Chikako, Tateishi, Takayuki, Yajima, Hiroyuki, Duong, Tina, Wolf, Brittney, Gee, Richard, Bharucha‐Goebel, Diana X., Bravver, Elena, Mori‐Yoshimura, Madoka, Bushby, Kate, Rufibach, Laura E., Straub, Volker, Lowes, Linda P.
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.08.2022; Wiley Subscription Services, Inc
• Subjects: dysferlinopathy; Evaluation; handheld dynamometry; Heterogeneity; limb girdle muscular dystrophy; Muscle strength; outcome measure; Patients; Reliability analysis; Sensitivity analysis; strength; Strength testing; Variability; outcome measure; handheld dynamometry; strength; limb girdle muscular dystrophy; dysferlinopathy

Introduction/Aims Dysferlinopathy demonstrates heterogeneity in muscle weakness between patients, which can progress at different rates over time. Changing muscle strength due to disease progression or from an investigational product is associated with changing functional ability. The purpose of thi...