Infection and the Risk of Spontaneous Cervical Artery Dissection A Case-Control Study
Background and Purpose— Several constitutional and environmental risk factors may be involved in the occurrence of spontaneous cervical artery dissection (SCAD). This work explored the association between recent infection and SCAD in an hospital-based case-control study. Methods— Forty-seven patient...
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Published in | Stroke (1970) Vol. 34; no. 7; p. e79 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
01.07.2003
|
Subjects | |
Online Access | Get full text |
ISSN | 0039-2499 1524-4628 1524-4628 |
DOI | 10.1161/01.STR.0000078309.56307.5C |
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Abstract | Background and Purpose—
Several constitutional and environmental risk factors may be involved in the occurrence of spontaneous cervical artery dissection (SCAD). This work explored the association between recent infection and SCAD in an hospital-based case-control study.
Methods—
Forty-seven patients with SCAD and 52 with ischemic stroke from another cause were prospectively and consecutively recruited by 2 neurology departments. A specially designed questionnaire was used to assess the history of an acute infection that could have occurred within a month before the vascular event.
Results—
Acute infection was more frequent in patients with SCAD (31.9%) than in control subjects (13.5%) (crude odds ratio, 3.0; 95% confidence interval, 1.1 to 8.2;
P
=0.032). This association was stronger in patients with multiple (odds ratio, 6.4) than single artery (odds ratio, 2.1) dissection.
Conclusions—
Recent infection is a risk factor and could be a trigger for SCAD. |
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AbstractList | Background and Purpose—
Several constitutional and environmental risk factors may be involved in the occurrence of spontaneous cervical artery dissection (SCAD). This work explored the association between recent infection and SCAD in an hospital-based case-control study.
Methods—
Forty-seven patients with SCAD and 52 with ischemic stroke from another cause were prospectively and consecutively recruited by 2 neurology departments. A specially designed questionnaire was used to assess the history of an acute infection that could have occurred within a month before the vascular event.
Results—
Acute infection was more frequent in patients with SCAD (31.9%) than in control subjects (13.5%) (crude odds ratio, 3.0; 95% confidence interval, 1.1 to 8.2;
P
=0.032). This association was stronger in patients with multiple (odds ratio, 6.4) than single artery (odds ratio, 2.1) dissection.
Conclusions—
Recent infection is a risk factor and could be a trigger for SCAD. Several constitutional and environmental risk factors may be involved in the occurrence of spontaneous cervical artery dissection (SCAD). This work explored the association between recent infection and SCAD in an hospital-based case-control study. Forty-seven patients with SCAD and 52 with ischemic stroke from another cause were prospectively and consecutively recruited by 2 neurology departments. A specially designed questionnaire was used to assess the history of an acute infection that could have occurred within a month before the vascular event. Acute infection was more frequent in patients with SCAD (31.9%) than in control subjects (13.5%) (crude odds ratio, 3.0; 95% confidence interval, 1.1 to 8.2; P=0.032). This association was stronger in patients with multiple (odds ratio, 6.4) than single artery (odds ratio, 2.1) dissection. Recent infection is a risk factor and could be a trigger for SCAD. Several constitutional and environmental risk factors may be involved in the occurrence of spontaneous cervical artery dissection (SCAD). This work explored the association between recent infection and SCAD in an hospital-based case-control study.BACKGROUND AND PURPOSESeveral constitutional and environmental risk factors may be involved in the occurrence of spontaneous cervical artery dissection (SCAD). This work explored the association between recent infection and SCAD in an hospital-based case-control study.Forty-seven patients with SCAD and 52 with ischemic stroke from another cause were prospectively and consecutively recruited by 2 neurology departments. A specially designed questionnaire was used to assess the history of an acute infection that could have occurred within a month before the vascular event.METHODSForty-seven patients with SCAD and 52 with ischemic stroke from another cause were prospectively and consecutively recruited by 2 neurology departments. A specially designed questionnaire was used to assess the history of an acute infection that could have occurred within a month before the vascular event.Acute infection was more frequent in patients with SCAD (31.9%) than in control subjects (13.5%) (crude odds ratio, 3.0; 95% confidence interval, 1.1 to 8.2; P=0.032). This association was stronger in patients with multiple (odds ratio, 6.4) than single artery (odds ratio, 2.1) dissection.RESULTSAcute infection was more frequent in patients with SCAD (31.9%) than in control subjects (13.5%) (crude odds ratio, 3.0; 95% confidence interval, 1.1 to 8.2; P=0.032). This association was stronger in patients with multiple (odds ratio, 6.4) than single artery (odds ratio, 2.1) dissection.Recent infection is a risk factor and could be a trigger for SCAD.CONCLUSIONSRecent infection is a risk factor and could be a trigger for SCAD. |
Author | Bertrand, Marion Tzourio, Christophe Berthet, Karine Benslamia, Lamia Bousser, Marie-Germaine Guillon, Benoît |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/12805497$$D View this record in MEDLINE/PubMed |
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Snippet | Background and Purpose—
Several constitutional and environmental risk factors may be involved in the occurrence of spontaneous cervical artery dissection... Several constitutional and environmental risk factors may be involved in the occurrence of spontaneous cervical artery dissection (SCAD). This work explored... |
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SubjectTerms | Acute Disease Adult Brain Ischemia - epidemiology Carotid Artery, Internal, Dissection - epidemiology Case-Control Studies Causality Comorbidity Female France - epidemiology Humans Infection - epidemiology Male Middle Aged Neck - blood supply Odds Ratio Risk Assessment Risk Factors Stroke - epidemiology Vertebral Artery Dissection - epidemiology |
Subtitle | A Case-Control Study |
Title | Infection and the Risk of Spontaneous Cervical Artery Dissection |
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