Phlorotannins from brown algae: a review on their antioxidant mechanisms and applications in oxidative stress-mediated diseases

• Published in: Journal of applied phycology Vol. 35; no. 2; pp. 867 - 892
• Main Authors: Phang, Shou Jin, Teh, Huey Xhin, Looi, Mee Lee, Arumugam, Bavani, Fauzi, Mh Busra, Kuppusamy, Umah Rani
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.04.2023; Springer Nature B.V
• Subjects: Algae; antioxidant activity; Antioxidant properties; Antioxidants; Bioavailability; Biocompatibility; Biomedical and Life Sciences; chemical structure; Defence mechanisms; diabetes; Diabetes mellitus; Diseases; Drug carriers; Drug delivery; drugs; Ecology; Encapsulation; Freshwater & Marine Ecology; In vivo methods and tests; Life Sciences; Liver diseases; Molecular structure; Nanofibers; Nanoparticles; Neurodegenerative diseases; Oxidation; Oxidative stress; Pathogenesis; Phaeophyceae; phenol; Phenols; phlorotannins; Plant Physiology; Plant Sciences; Polyphenols; Reactive oxygen species; Scavenging; Skin diseases; therapeutics; Oxidative stress; Liver diseases; Neurodegenerative diseases; Anti-oxidant; Skin diseases; Diabetes; Antioxidant; Retinal diseases; Phlorotannins; Phaeophyceae

Phlorotannins are polyphenolic compounds that are exclusively derived from marine brown algae. The molecular structure of phlorotannins with numerous phenol rings endows them with excellent radical scavenging and antioxidant properties. Oxidative stress plays a central role in the pathogenesis of ma...