Feasibility of arresting the process of remodeling

• Published in: The Medical clinics of North America Vol. 88; no. 5; p. 1193
• Main Authors: Somasundaram, P E, Chandrashekhar, Y
• Format: Journal Article
• Language: English
• Published: United States 01.09.2004
• Subjects: Adrenergic beta-Antagonists - therapeutic use; Angiotensin-Converting Enzyme Inhibitors - therapeutic use; Calcium Channel Blockers - therapeutic use; Cardiac Pacing, Artificial; Cardiomyoplasty; Cardiotonic Agents - therapeutic use; Disease Progression; Feasibility Studies; Heart Failure - complications; Heart Failure - mortality; Heart Failure - physiopathology; Heart Failure - prevention & control; Heart-Assist Devices; Humans; Patient Selection; Philosophy, Medical; Predictive Value of Tests; Risk Factors; Salvage Therapy - methods; Survival Analysis; Treatment Outcome; Ventricular Remodeling - drug effects; Ventricular Remodeling - physiology

Heart failure (HF) is a massive public health issue. Ventricular remodeling is pivotal to the pathophysiology/progression of HF and an attractive target for intervention. It currently is believed that interdicting the natural history of ventricular remodeling will be crucial to controlling the HF ep...