Screening of Lactobacillus strains that enhance SCFA uptake in intestinal epithelial cells

• Published in: European food research & technology Vol. 247; no. 5; pp. 1049 - 1060
• Main Authors: Chen, Da-wei, Chen, Chun-meng, Qu, Heng-xian, Ren, Chen-yu, Yan, Xian-tao, Huang, Yu-jun, Guan, Cheng-ran, Zhang, Chen-chen, Li, Qi-ming, Gu, Rui-xia
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.05.2021; Springer Nature B.V
• Subjects: Absorption; Adhesion; Agriculture; Analytical Chemistry; Biotechnology; Butyric acid; Chemistry; Chemistry and Materials Science; Epithelial cells; Epithelium; Fatty acids; Food; food research; Food Science; Forestry; Gastrointestinal system; Gastrointestinal tract; human cell lines; Inoculation; Intestine; Lactobacillus; Lactobacillus fermentum; Lactobacillus plantarum; Membrane permeability; Metabolism; Model testing; Mucin; Mucins; Original Paper; Pathogens; Permeability; Permeability coefficient; Phenols; phenolsulfonphthalein; Plant cells; Propionic acid; Survivability; Survival; survival rate; technology; Tight junctions; viability; Scfas; Oro-gastrointestinal stress; Caco-2 cells; Adhesion

The objective was to screen Lactobacillus strains with strong survivability in oro-gastrointestinal tract and adhesion abilities of intestinal mucins and Caco-2 cells, and their effect on absorption of short-chain fatty acids (SCFAs) by epithelial cells was studied. The survival rate of Lactobacillu...