Sex-related differences in upper limb motor function in healthy subjects and multiple sclerosis patients: a multiparametric MRI study

• Published in: Journal of neurology Vol. 270; no. 11; pp. 5235 - 5250
• Main Authors: Bonacchi, Raffaello, Valsasina, Paola, Pagani, Elisabetta, Meani, Alessandro, Preziosa, Paolo, Rocca, Maria A., Filippi, Massimo
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2023; Springer Nature B.V
• Subjects: Anisotropy; Cerebellum; Cognitive ability; Females; Gender differences; Magnetic resonance imaging; Males; Medicine; Medicine & Public Health; Motor task performance; Multiple sclerosis; Neural networks; Neurology; Neuroradiology; Neurosciences; Original Communication; Sensorimotor system; Sex; Sex differences; Substantia alba; Substantia grisea; Gender medicine; Magnetic resonance imaging; Multiple sclerosis

Background We investigated sex-related differences in upper limb motor performance tested with the 9-Hole Peg Test (9HPT) in healthy controls (HC) and multiple sclerosis (MS) patients and their MRI substrates. Materials and methods We enrolled 94 HC and 133 MS patients, who underwent neurological ex...