Global stability of SAIRS epidemic models

We study an SAIRS-type epidemic model with vaccination, where the role of asymptomatic and symptomatic infectious individuals is explicitly considered in the transmission patterns of the disease. We provide a global stability analysis for the model. We determine the value of the basic reproduction n...

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Published inNonlinear analysis: real world applications Vol. 65; p. 103501
Main Authors Ottaviano, Stefania, Sensi, Mattia, Sottile, Sara
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.06.2022
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Abstract We study an SAIRS-type epidemic model with vaccination, where the role of asymptomatic and symptomatic infectious individuals is explicitly considered in the transmission patterns of the disease. We provide a global stability analysis for the model. We determine the value of the basic reproduction number R0 and prove that the disease-free equilibrium is globally asymptotically stable if R0<1. If R0>1, the disease free equilibrium is unstable and a unique endemic equilibrium exists. We investigate the global stability of the endemic equilibrium for some variations of the original model under study and answer an open problem proposed in Ansumali et al. (2020). In the case of the SAIRS model without vaccination, we prove the global asymptotic stability of the disease-free equilibrium also when R0=1. We provide a thorough numerical exploration of our model to illustrate our analytical results.
AbstractList We study an SAIRS-type epidemic model with vaccination, where the role of asymptomatic and symptomatic infectious individuals is explicitly considered in the transmission patterns of the disease. We provide a global stability analysis for the model. We determine the value of the basic reproduction number R0 and prove that the disease-free equilibrium is globally asymptotically stable if R0<1. If R0>1, the disease free equilibrium is unstable and a unique endemic equilibrium exists. We investigate the global stability of the endemic equilibrium for some variations of the original model under study and answer an open problem proposed in Ansumali et al. (2020). In the case of the SAIRS model without vaccination, we prove the global asymptotic stability of the disease-free equilibrium also when R0=1. We provide a thorough numerical exploration of our model to illustrate our analytical results.
ArticleNumber 103501
Author Sottile, Sara
Sensi, Mattia
Ottaviano, Stefania
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Keywords Susceptible–asymptomatic infected–symptomatic infected–recovered–susceptible
Geometric approach
Global asymptotic stability
Basic reproduction number
Lyapunov functions
Vaccination
Language English
License This is an open access article under the CC BY license.
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Snippet We study an SAIRS-type epidemic model with vaccination, where the role of asymptomatic and symptomatic infectious individuals is explicitly considered in the...
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StartPage 103501
SubjectTerms Basic reproduction number
Geometric approach
Global asymptotic stability
Lyapunov functions
Susceptible–asymptomatic infected–symptomatic infected–recovered–susceptible
Vaccination
Title Global stability of SAIRS epidemic models
URI https://dx.doi.org/10.1016/j.nonrwa.2021.103501
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