The cardiotoxicity of asthmatic rats after traffic-related PM2.5 and water-soluble components exposure mediated by endoplasmic reticulum stress and autophagy

• Published in: Environmental science and pollution research international Vol. 29; no. 33; pp. 50704 - 50716
• Main Authors: Tian, Jiayu, Shi, Hao, Wang, Xin, Wu, Hongyan, Wang, Caihong, Liu, Nannan, Wang, Dan, Shi, Dongxing, Zhang, Hongmei, Zhang, Zhihong
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2022; Springer Nature B.V
• Subjects: Apoptosis; Aquatic Pollution; Asthma; Atmospheric Protection/Air Quality Control/Air Pollution; Autophagy; Cardiotoxicity; Cardiovascular system; Caspase-12; DNA nucleotidylexotransferase; Earth and Environmental Science; Ecotoxicology; Endoplasmic reticulum; Environment; Environmental Chemistry; Environmental Health; Environmental science; Gene expression; Molecular modelling; Ovalbumin; Particulate matter; Research Article; Respiratory system; Signal transduction; Transient receptor potential proteins; Waste Water Technology; Water chemistry; Water Management; Water Pollution Control; Traffic-related PM; Cardiotoxicity; Autophagy; Water-soluble components; Asthma; Endoplasmic reticulum stress; Apoptosis

Fine particulate matter (PM 2.5 ) is closely related to cardiopulmonary diseases; it is known that the respiratory system is related to the cardiovascular system. This study aimed to investigate the toxic effects of traffic-related PM 2.5 (TRPM 2.5 ) and water-soluble components (WSC) on hearts of a...