Localization of central pressor action of bradykinin in medulla oblongata

• Published in: The American journal of physiology Vol. 265; no. 3 Pt 2; p. H1000
• Main Authors: Fior, D R, Martins, D T, Lindsey, C J
• Format: Journal Article
• Language: English
• Published: United States 01.09.1993
• Subjects: Animals; Blood Pressure - drug effects; Blood Pressure - physiology; Bradykinin - pharmacology; Cerebral Ventricles - physiology; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Medulla Oblongata - physiology; Rats; Rats, Wistar

The intracerebroventricular injection of bradykinin produces an increase in arterial blood pressure. The site of action for this effect has been reported to be in the lateral septal area, in the hypothalamus, or in the ventral portion of the third ventricle. Bradykinin injected into the fourth cereb...