Antibody engagement with amyloid‐beta does not inhibit [11C]PiB binding for PET imaging - Xiong, Mengfei; Dahlén, Amelia; Roshanbin, Sahar; Wik, Elin; Aguilar, Ximena; Eriksson, Jonas; Sehlin, Dag; Syvänen, Stina (Journal of neurochemistry, 2024)
Keywords: [11C]PiB; Aggregates; Alzheimer Disease - diagnostic imaging; Alzheimer Disease - metabolism; Alzheimer's disease; Alzheimer's disease (AD); Amyloid beta-Peptides - immunology; Amyloid beta-Peptides - metabolism; amyloid PET; amyloid‐beta; Aniline Compounds - pharmacology; Animals; Antibodies; Antibodies, Monoclonal - pharmacology; Antibodies, Monoclonal, Humanized - pharmacology; antibody treatment; Autoradiography; Benzothiazoles - pharmacology; Binding; Brain; Brain - diagnostic imaging; Brain - drug effects; Brain - metabolism; Carbon Radioisotopes; Cognitive ability; Female; Health services; Humans; immunotherapy; Male; Medical imaging; Mice; Mice, Transgenic; Monoclonal antibodies; Myeloid cells; Neurodegenerative diseases; Neuroimaging; Patients; Plaque, Amyloid - diagnostic imaging; Plaque, Amyloid - metabolism; Positron emission; Positron emission tomography; Positron-Emission Tomography - methods; Radiopharmaceuticals; Senile plaques; Thiazoles - pharmacology; β-Amyloid; [11C]PiB; Alzheimer's disease (AD); antibody treatment; immunotherapy; amyloid PET; amyloid‐beta