Gastric cancer risk in the elderly is associated with omeprazole use and inversely associated with aspirin use

• Published in: European journal of gastroenterology & hepatology Vol. 35; no. 9; p. 968
• Main Authors: Gingold-Belfer, Rachel, Issa, Nidal, Boltin, Doron, Beloosesky, Yichayaou, Koren-Morag, Nira, Meyerovitch, Joseph, Sharon, Eran, Peleg, Noam, Schmilovitz-Weiss, Hemda
• Format: Journal Article
• Language: English
• Published: England 01.09.2023
• Subjects: Aged; Anti-Inflammatory Agents, Non-Steroidal - adverse effects; Aspirin - adverse effects; Humans; Omeprazole - adverse effects; Risk; Stomach Neoplasms - chemically induced; Stomach Neoplasms - epidemiology; Stomach Neoplasms - prevention & control

The association between long-term omeprazole use and gastric cancer (GC) risk is controversial. The aim of this study was to investigate the incidence of GC in elderly community-dwelling omeprazole chronic users with/without aspirin compared to non-users. The registry of a large health management or...