Immune Checkpoint Inhibition in Marjolin Ulcer: A Case Series

• Published in: Journal of immunotherapy (1997) Vol. 44; no. 6; p. 234
• Main Authors: Shalhout, Sophia Z, Kaufman, Howard L, Sullivan, Ryan J, Lawrence, Donald, Miller, David M
• Format: Journal Article
• Language: English
• Published: United States 01.07.2021
• Subjects: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Combined Modality Therapy; Diagnostic Imaging; Female; Humans; Immune Checkpoint Inhibitors - administration & dosage; Immune Checkpoint Inhibitors - adverse effects; Immune Checkpoint Inhibitors - therapeutic use; Male; Middle Aged; Molecular Targeted Therapy - adverse effects; Molecular Targeted Therapy - methods; Neoplasm Grading; Neoplasm Staging; Retreatment; Retrospective Studies; Skin Neoplasms - diagnosis; Skin Neoplasms - drug therapy; Skin Neoplasms - etiology; Treatment Outcome; Ulcer - diagnosis; Ulcer - drug therapy; Ulcer - etiology

Immunotherapy has revolutionized the treatment of advanced cutaneous squamous cell carcinoma. However, the role of immune checkpoint inhibitors for the treatment of Marjolin ulcer (MU), a rare cutaneous malignancy that arises from previously traumatized and chronically inflamed skin, is not well def...