Recent explanatory trials of the mode of action of drug therapies on lipoprotein metabolism

• Published in: Current opinion in lipidology Vol. 27; no. 6; p. 550
• Main Authors: Chan, Dick C, Barrett, P Hugh R, Watts, Gerald F
• Format: Journal Article
• Language: English
• Published: England 01.12.2016
• Subjects: Clinical Trials as Topic - methods; Drug Therapy - methods; Humans; Kinetics; Lipoproteins - metabolism

Dysregulated lipoprotein metabolism leads to increased plasma concentrations of atherogenic lipoproteins. We highlight the findings from recent studies of the effect of lipid-regulating therapies on apolipoprotein metabolism in humans employing endogenous labelling with stable isotopically labelled...