Healing Human Moderate and Large Traumatic Tympanic Membrane Perforations Using Basic Fibroblast Growth Factor, 0.3% Ofloxacin Eardrops, and Gelfoam Patching

• Published in: Otology & neurotology Vol. 37; no. 6; p. 735
• Main Authors: Lou, Zheng-Cai, Lou, Zi-Han, Liu, Ya-Chao, Chang, Jiang
• Format: Journal Article
• Language: English
• Published: United States 01.07.2016
• Subjects: Adult; Anti-Bacterial Agents - therapeutic use; Female; Fibroblast Growth Factor 2 - therapeutic use; Gelatin Sponge, Absorbable - therapeutic use; Humans; Male; Middle Aged; Ofloxacin - therapeutic use; Prospective Studies; Treatment Outcome; Tympanic Membrane - drug effects; Tympanic Membrane Perforation - drug therapy; Wound Healing - drug effects; Young Adult

The goal of this study was to evaluate the effects of basic fibroblast growth factor (bFGF), 0.3% ofloxacin eardrops (OFLX), and Gelfoam patching on the healing of human moderate and large traumatic tympanic membrane perforations (TMPs). A prospective, quasi-randomized, controlled clinical study. A...