Genome wide association study gateway—transitioning variants from association to causality in complex diseases
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| Published in | Sleep (New York, N.Y.) Vol. 47; no. 7; p. 1 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
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Oxford University Press
11.07.2024
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| Online Access | Get full text |
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| Audience | Academic |
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| Author | Zhao, Chen |
| Author_xml | – sequence: 1 givenname: Chen surname: Zhao fullname: Zhao, Chen email: chen.zhao@helmholtz-munich.de |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/38752386$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1038/nrg2149 10.1007/s00439-013-1331-2 10.1038/s41467-019-08917-4 10.1038/s41588-018-0333-3 10.1038/nrg3118 10.1038/nrg3461 10.1126/science.aaz1776 10.1038/s41594-022-00896-3 10.3389/fgene.2020.00424 10.1038/s41576-018-0016-z 10.1126/science.abo1131 10.1126/sciadv.abq0844 10.1038/s41576-019-0128-0 10.1126/science.abi8207 10.1093/sleep/zsae085 10.1038/s41582-020-0373-z 10.1038/nature13127 |
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| Copyright | The Author(s) 2024. Published by Oxford University Press on behalf of Sleep Research Society. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com. 2024 COPYRIGHT 2024 Oxford University Press The Author(s) 2024. Published by Oxford University Press on behalf of Sleep Research Society. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com. |
| Copyright_xml | – notice: The Author(s) 2024. Published by Oxford University Press on behalf of Sleep Research Society. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com. 2024 – notice: COPYRIGHT 2024 Oxford University Press – notice: The Author(s) 2024. Published by Oxford University Press on behalf of Sleep Research Society. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com. |
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| DOI | 10.1093/sleep/zsae116 |
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| References | Fiziev (2024071105520544200_CIT0005) 2023; 380 Solovieff (2024071105520544200_CIT0016) 2013; 14 Cano-Gamez (2024071105520544200_CIT0018) 2020; 11 Gibson (2024071105520544200_CIT0001) 2012; 13 Beckmann (2024071105520544200_CIT0006) 2007; 8 MacArthur (2024071105520544200_CIT0009) 2014; 508 Zaugg (2024071105520544200_CIT0017) 2022; 29 Dashti (2024071105520544200_CIT0014) 2019; 10 Cooper (2024071105520544200_CIT0004) 2013; 132 Schoenfelder (2024071105520544200_CIT0012) 2019; 20 Aguet (2024071105520544200_CIT0013) 2020; 369 Kampmann (2024071105520544200_CIT0008) 2020; 16 Sonti (2024071105520544200_CIT0010) 2024; 47 Schaid (2024071105520544200_CIT0007) 2018; 19 Lewontin (2024071105520544200_CIT0003) 1974; 26 Palermo (2024071105520544200_CIT0011) 2023; 9 Jansen (2024071105520544200_CIT0015) 2019; 51 Lappalainen (2024071105520544200_CIT0002) 2021; 373 38571402 - Sleep. 2024 Jul 11;47(7):zsae085. doi: 10.1093/sleep/zsae085. |
| References_xml | – volume: 8 start-page: 639 issue: 8 year: 2007 ident: 2024071105520544200_CIT0006 article-title: Copy number variants and genetic traits: closer to the resolution of phenotypic to genotypic variability publication-title: Nat Rev Genet. doi: 10.1038/nrg2149 – volume: 132 start-page: 1077 issue: 10 year: 2013 ident: 2024071105520544200_CIT0004 article-title: Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease publication-title: Hum Genet. doi: 10.1007/s00439-013-1331-2 – volume: 10 start-page: 1100 issue: 1 year: 2019 ident: 2024071105520544200_CIT0014 article-title: Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates publication-title: Nat Commun. doi: 10.1038/s41467-019-08917-4 – volume: 51 start-page: 394 issue: 3 year: 2019 ident: 2024071105520544200_CIT0015 article-title: Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways publication-title: Nat Genet. doi: 10.1038/s41588-018-0333-3 – volume: 13 start-page: 135 issue: 2 year: 2012 ident: 2024071105520544200_CIT0001 article-title: Rare and common variants: twenty arguments publication-title: Nat Rev Genet. doi: 10.1038/nrg3118 – volume: 14 start-page: 483 issue: 7 year: 2013 ident: 2024071105520544200_CIT0016 article-title: Pleiotropy in complex traits: challenges and strategies publication-title: Nat Rev Genet. doi: 10.1038/nrg3461 – volume: 26 start-page: 400 issue: 3 year: 1974 ident: 2024071105520544200_CIT0003 article-title: Annotation: the analysis of variance and the analysis of causes publication-title: Am J Hum Genet. – volume: 369 start-page: 1318 issue: 6509 year: 2020 ident: 2024071105520544200_CIT0013 article-title: The GTEx Consortium atlas of genetic regulatory effects across human tissues publication-title: Science doi: 10.1126/science.aaz1776 – volume: 29 start-page: 1148 issue: 12 year: 2022 ident: 2024071105520544200_CIT0017 article-title: Current challenges in understanding the role of enhancers in disease publication-title: Nat Struct Mol Biol. doi: 10.1038/s41594-022-00896-3 – volume: 11 start-page: 424 year: 2020 ident: 2024071105520544200_CIT0018 article-title: From GWAS to function: using functional genomics to identify the mechanisms underlying complex diseases publication-title: Front Genet. doi: 10.3389/fgene.2020.00424 – volume: 19 start-page: 491 issue: 8 year: 2018 ident: 2024071105520544200_CIT0007 article-title: From genome-wide associations to candidate causal variants by statistical fine-mapping publication-title: Nat Rev Genet. doi: 10.1038/s41576-018-0016-z – volume: 380 start-page: eabo1131 issue: 6648 year: 2023 ident: 2024071105520544200_CIT0005 article-title: Rare penetrant mutations confer severe risk of common diseases publication-title: Science. doi: 10.1126/science.abo1131 – volume: 9 start-page: eabq0844 issue: 1 year: 2023 ident: 2024071105520544200_CIT0011 article-title: Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep publication-title: Sci Adv. doi: 10.1126/sciadv.abq0844 – volume: 20 start-page: 437 issue: 8 year: 2019 ident: 2024071105520544200_CIT0012 article-title: Long-range enhancer-promoter contacts in gene expression control publication-title: Nat Rev Genet. doi: 10.1038/s41576-019-0128-0 – volume: 373 start-page: 1464 issue: 6562 year: 2021 ident: 2024071105520544200_CIT0002 article-title: From variant to function in human disease genetics publication-title: Science doi: 10.1126/science.abi8207 – volume: 47 issue: 7 year: 2024 ident: 2024071105520544200_CIT0010 article-title: Perturbation of the insomnia WDR90 GWAS locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q publication-title: Sleep doi: 10.1093/sleep/zsae085 – volume: 16 start-page: 465 issue: 9 year: 2020 ident: 2024071105520544200_CIT0008 article-title: CRISPR-based functional genomics for neurological disease publication-title: Nat Rev Neurol. doi: 10.1038/s41582-020-0373-z – volume: 508 start-page: 469 issue: 7497 year: 2014 ident: 2024071105520544200_CIT0009 article-title: Guidelines for investigating causality of sequence variants in human disease publication-title: Nature. doi: 10.1038/nature13127 – reference: 38571402 - Sleep. 2024 Jul 11;47(7):zsae085. doi: 10.1093/sleep/zsae085. |
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| SubjectTerms | Causality Diseases Genetic aspects Genetic Predisposition to Disease - genetics Genetic research Genome-Wide Association Study Genomics Germany Humans Single nucleotide polymorphisms |
| Title | Genome wide association study gateway—transitioning variants from association to causality in complex diseases |
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