Gene Expression Profiling with DNA Microarrays: Advancing Our Understanding of Psychiatric Disorders

• Published in: Neurochemical research Vol. 27; no. 10; pp. 1049 - 1063
• Main Authors: Pongrac, Julie, Middleton, Frank A., Lewis, David A., Levitt, Pat, Mirnics, Károly
• Format: Journal Article
• Language: English
• Published: United States Springer Nature B.V 01.10.2002
• Subjects: Brain - physiopathology; Gene Expression Profiling - methods; Humans; Mental Disorders - genetics; Mental Disorders - physiopathology; Oligonucleotide Array Sequence Analysis; Schizophrenia - genetics; Schizophrenia - physiopathology; Synapses - physiology

DNA microarray transcriptome profiling of the postmortem brain opens novel horizons in understanding molecular changes associated with complex psychiatric disorders. With careful analysis and interpretation of microarray data we are uncovering previously unknown, expression patterns that maybe subje...