Increased odds of necrotizing enterocolitis after transfusion of red blood cells in premature infants

• Published in: Pediatrics (Evanston) Vol. 127; no. 4; p. 635
• Main Authors: Paul, David A, Mackley, Amy, Novitsky, Alexandra, Zhao, Yong, Brooks, Alison, Locke, Robert G
• Format: Journal Article
• Language: English
• Published: United States 01.04.2011
• Subjects: Anemia, Neonatal - epidemiology; Anemia, Neonatal - therapy; Cohort Studies; Cross-Sectional Studies; Delaware; Enterocolitis, Necrotizing - epidemiology; Enterocolitis, Necrotizing - etiology; Erythrocyte Transfusion - adverse effects; Erythrocyte Transfusion - statistics & numerical data; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature, Diseases - epidemiology; Infant, Premature, Diseases - etiology; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Male; Odds Ratio; Retrospective Studies; Risk Factors; Statistics as Topic; Delaware

To determine if infants with very low birth weight who receive packed red blood cell (PRBC) transfusions have increased odds of developing necrotizing enterocolitis (NEC), to determine the rate of NEC after PRBC transfusion, and to characterize the blood transfused preceding the onset of NEC. A retr...