Neuroprotective effects of compounds interacting with carrier-mediated amantadine transport across the blood–retinal barrier in rats - Shinozaki, Yusuke; Akanuma, Shin-ichi; Tega, Yuma; Hosoya, Ken-ichi (Journal of pharmacological sciences, 2025)
Keywords: Adamantane - analogs & derivatives; Adamantane - pharmacology; Amantadine; Amantadine - administration & dosage; Amantadine - analogs & derivatives; Amantadine - metabolism; Amantadine - pharmacokinetics; Amantadine - pharmacology; Animals; Biological Transport - drug effects; Blood-Retinal Barrier - metabolism; Blood–retinal barrier; Cells, Cultured; Drug delivery; Male; Neurons - drug effects; Neurons - metabolism; Neuroprotection; Neuroprotective Agents - metabolism; Neuroprotective Agents - pharmacology; Rats; Rats, Sprague-Dawley; Retina - metabolism; Retinal disease; Retinal Diseases - drug therapy; Neuroprotection; Amantadine; Drug delivery; Blood–retinal barrier; Retinal disease