Asymmetric Synthesis of Cyclic Alkenes via Cyclization of Enantioenriched Allylsilanes

• Published in: Synlett Vol. 2001; no. Special Issue; pp. 1042 - 1045
• Main Authors: Suginome, Michinori, Iwanami, Taisuke, Yamamoto, Akihiko, Ito, Yoshihiko
• Format: Journal Article
• Language: English
• Published: STUTTGART Thieme Medical Publishers 2001
• Subjects: Chemistry; Chemistry, Organic; letter; Physical Sciences; Science & Technology; Lewis acids; allylations; silicon; chirality transfer; stereoselective synthesis; OPTICALLY-ACTIVE ALLYLSILANES; MEDIATED CARBOCYCLIZATION; ALDEHYDES; INTRAMOLECULAR BIS-SILYLATION

Intramolecular cyclizations of optically active allylsilanes bearing electrophilic functional groups on their alpha -alkyl side chains were examined. The allylsilanes having aldehyde and enone functional groups underwent the intramolecular cyclizations in the presence of Lewis acid catalysts to give...