Recent advances in generative biology for biotherapeutic discovery

• Published in: Trends in pharmacological sciences (Regular ed.) Vol. 45; no. 3; pp. 255 - 267
• Main Authors: Mock, Marissa, Langmead, Christopher James, Grandsard, Peter, Edavettal, Suzanne, Russell, Alan
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.03.2024
• Subjects: Artificial Intelligence; biologics; Biology; drug discovery; Drug Discovery - methods; generative biology; Humans; machine learning; multispecifics; protein engineering; multispecifics; protein engineering; biologics; drug discovery; machine learning; generative biology

Protein therapeutics are an important and growing class of medicine with discovery and development cycles that are long, expensive, and frequently unsuccessful.The current wave of drug development is dominated by multispecific drugs, which can achieve impressive therapeutic efficacy by interacting w...