A new family with dexamethasone-suppressible hyperaldosteronism: aldosterone unresponsiveness to angiotensin II

• Published in: Clinical endocrinology (Oxford) Vol. 22; no. 6; p. 777
• Main Authors: Fallo, F, Sonino, N, Armanini, D, Luzzi, T, Pedini, F, Pasini, C, Mantero, F
• Format: Journal Article
• Language: English
• Published: England 01.06.1985
• Subjects: Adrenocorticotropic Hormone - therapeutic use; Adult; Aged; Aldosterone - blood; Angiotensin II - therapeutic use; Blood Pressure; Dexamethasone - therapeutic use; Female; Humans; Hydrocortisone - blood; Hyperaldosteronism - blood; Hyperaldosteronism - drug therapy; Hyperaldosteronism - genetics; Male; Pedigree; Renin - blood

A family with nine siblings in which three siblings have been shown to have dexamethasone-suppressible hyperaldosteronism was studied. All three showed no significant changes of plasma aldosterone during angiotensin II infusion at incremental rates under baseline conditions. After dexamethasone admi...