Taylor dispersion monitored by electrospray mass spectrometry: a novel approach for studying diffusion in solution

• Published in: Rapid communications in mass spectrometry Vol. 16; no. 15; pp. 1454 - 1462
• Main Authors: Clark, Sonya M., Leaist, Derek G., Konermann, Lars
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.01.2002
• Subjects: Algorithms; Choline - chemistry; Convection; Cytochrome c Group - chemistry; Diffusion; Solutions; Spectrometry, Mass, Electrospray Ionization - methods

This work describes a novel approach for monitoring analyte diffusion in solution that is based on electrospray ionization mass spectrometry (ESI‐MS). A mass spectrometer at the end of a laminar flow tube is used to measure the Taylor dispersion of an initially sharp boundary between two solutions o...