LncRNA SLC7A11-AS1 promotes the progression of hepatocellular carcinoma by mediating KLF9 ubiquitination

• Published in: Neoplasma Vol. 70; no. 3; p. 361
• Main Authors: Zeng, Fan-Lin, Lin, Jie, Xie, Xing, Xie, Yuan-Kang, Zhang, Jian-Hong, Xu, Daofeng, He, Xiao, Liu, Feng En, Xie, Bin-Hui
• Format: Journal Article
• Language: English
• Published: Slovakia 01.06.2023
• Subjects: Animals; Carcinoma, Hepatocellular - pathology; Cell Line, Tumor; Cell Proliferation - genetics; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms - pathology; Mice; Mice, Nude; MicroRNAs - genetics; Proto-Oncogene Proteins c-akt - metabolism; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism

Hepatocellular carcinoma (HCC) is a malignant tumor, which seriously threatens the life of patients. LncRNA SLC7A11-AS1 was reported to be abnormally expressed in HCC. Here, the functions and relative molecular regulatory mechanism of SLC7A11-AS1 in HCC were investigated. Nude mice and HCC cells wer...