Role of apoptosis resistance in immune evasion and metastasis of colorectal cancer

• Published in: World journal of gastrointestinal oncology Vol. 2; no. 11; pp. 399 - 406
• Main Author: Liu, Kebin
• Format: Journal Article
• Language: English
• Published: China Baishideng Publishing Group Co., Limited 15.11.2010
• Subjects: Apoptosis; evasion; Fas; Immune; Metastasis; Fas; Immune evasion; Metastasis; Apoptosis

The host immune system functions as a guardian against tumor development. It has been demonstrated that cytotoxic T lymphocyte (CTL)-mediated cytotoxic pathways function to inhibit or delay human colorectal cancer development. However, the host anti-tumor immune responses also ’edit’ the tumor and s...