Amino acid metabolomics and machine learning for assessment of post-hepatectomy liver regeneration

• Published in: Frontiers in pharmacology Vol. 15; p. 1345099
• Main Authors: Yan, Yuqing, Chen, Qianping, Dai, Xiaoming, Xiang, Zhiqiang, Long, Zhangtao, Wu, Yachen, Jiang, Hui, Zou, Jianjun, Wang, Mu, Zhu, Zhu
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 24.05.2024
• Subjects: hepatectomy; liver regeneration; machine learning; metabolomics; non-alcoholic steatohepatitis (NASH); Pharmacology; hepatectomy; machine learning; metabolomics; liver regeneration; non-alcoholic steatohepatitis (NASH)

Amino acid (AA) metabolism plays a vital role in liver regeneration. However, its measuring utility for post-hepatectomy liver regeneration under different conditions remains unclear. We aimed to combine machine learning (ML) models with AA metabolomics to assess liver regeneration in health and non...