Effects of mycotoxins in cultured kidney cells: cytotoxicity of aflatoxin B1 in madin-darby and primary fetal bovine kidney cells

• Published in: Ecotoxicology and environmental safety Vol. 13; no. 2; p. 174
• Main Authors: Yoneyama, M, Sharma, R.P, Elsner, Y.Y
• Format: Journal Article
• Language: English
• Published: Netherlands 01.04.1987
• Subjects: Aflatoxin B1; Aflatoxins - toxicity; Animals; Cattle; CELL CULTURE; Cell Survival - drug effects; Cells, Cultured; CULTIVO DE CELULAS; CULTURE DE CELLULES; FOOD HYGIENE; HIGIENE DE LOS ALIMENTOS; HYGIENE DES ALIMENTS; Kidney; MICOTOXINAS; Microscopy, Electron; Microscopy, Electron, Scanning; MYCOTOXINE; MYCOTOXINS; Mycotoxins - toxicity

The cytotoxicity of aflatoxin B1, a fungal metabolite and an important food contaminant, was evaluated in an established cell line, Madin-Darby bovine kidney (MDBK) cells, and in primary fetal bovine kidney (PFBK) cells. Cells were grown in monolayers and treated with media containing AFB1 for 24 hr...