Naked-eye detection of specific DNA sequences amplified by the polymerase chain reaction with nanocomposite beads

• Published in: Analytical biochemistry Vol. 617; p. 114114
• Main Authors: Tani, Hidenori, Yamaguchi, Masahiro, Enomoto, Yasushi, Matsumura, Yasufumi, Habe, Hiroshi, Nakazato, Tetsuya, Kurata, Shinya
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.03.2021
• Subjects: DNA probes; Naked-eye; Nanocomposite beads; PCR; Specific DNA sequences; Specific DNA sequences; Nanocomposite beads; DNA probes; Naked-eye; PCR

We developed a novel nanocomposite bead system for detection by the naked eye of specific DNA sequences amplified by the polymerase chain reaction (PCR). The DNA probes, which were complementary to the target DNA, are conjugated with the nanocomposite beads. If the amplified products contained seque...