Biocompatible and photoluminescent keratin/poly(vinyl alcohol)/carbon quantum dot nanofiber: A novel multipurpose electrospun mat

• Published in: Macromolecular research Vol. 24; no. 10; pp. 924 - 930
• Main Authors: Lee, Chohye, Pant, Bishweshwar, Alam, Al-Mahmnur, An, Taehee, Chung, Hea-Jong, Hong, Seong-Tshool, Park, Soo-Jin, Park, Mira, Kim, Hak-Yong
• Format: Journal Article
• Language: English
• Published: Seoul The Polymer Society of Korea 01.10.2016; Springer Nature B.V; 한국고분자학회
• Subjects: Biocompatibility; Carbon dots; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Complex Fluids and Microfluidics; Electron microscopes; Electron microscopy; Electrospinning; Emission spectra; Emission spectroscopy; Excitation spectra; Fourier transforms; Infrared spectroscopy; Keratin; Microscopy; Nanochemistry; Nanofibers; Nanotechnology; Photoluminescence; Physical Chemistry; Polymer Sciences; Polyvinyl alcohol; Quantum confinement; Quantum dots; Room temperature; Soft and Granular Matter; Spectral emittance; Spectrum analysis; Temperature dependence; Wavelengths; 고분자공학; keratin; photoluminescence; electrospinning; biocompatibility; poly(vinyl alcohol); carbon quantum dots
• DOI: 10.1007/s13233-016-4124-3
• ISSN: 1598-5032

Carbon quantum dots (C-dots) triggered photoluminescent keratin/poly(vinyl alcohol) (PVA)/C-dots nanofibers (NFs) with optical transparency and biocompatibility were prepared by an electrospinning process. The synthesized NFs were characterized by field-emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), ultraviolet-visible spectroscopy, and spectrofluorometer. C-dots are capable of emitting excitation dependent photoluminescence (PL) emission spectra at room temperature and are nontoxic at reasonably high concentrations. Optically transparent keratin/PVA/C-dots NFs were found to exhibit excitation dependent PL emission at the wavelengths of 488, 535, and 625 nm during excitation at the wavelengths of 360, 480, and 545 nm, respectively, similar to the C-dots. In vitro cytotoxicity tests against NIH-3T3 cell lines revealed a good biocompatible nature of keratin/PVA/C-dots. The results indicated that the fabricated composite NFs mat not only exhibited a well preserved quantum confinement effect of the C-dots along with its transparency but also showed biocompatibility in the living cell environment.