The inflammatory response of eosinophil-related fungal rhinosinusitis varies with inciting fungi

• Published in: Medical mycology (Oxford) Vol. 53; no. 4; p. 387
• Main Authors: Kale, Pratibha, Rudramurthy, Shivaprakash M, Panda, Naresh K, Das, Ashim, Chakrabarti, Arunaloke
• Format: Journal Article
• Language: English
• Published: England 01.05.2015
• Subjects: Adolescent; Adult; Asia; Aspergillosis - immunology; Aspergillosis - microbiology; Aspergillosis - pathology; Aspergillus - classification; Aspergillus - growth & development; Cell Degranulation; Child; Cytokines - blood; Cytokines - secretion; Eosinophils - immunology; Female; Humans; Immunoglobulin E - blood; Inflammation - immunology; Inflammation - pathology; Male; Middle Aged; Sinusitis - immunology; Sinusitis - microbiology; Sinusitis - pathology; Young Adult; Asia; allergy; eosinophils; cytokines; Aspergillus flavus; Alternaria alternata; fungal rhinosinusitis

Earlier studies demonstrated immunological response to Alternaria alternata in patients with eosinophil-related fungal rhinosinusitis (FRS). However, Aspergillus flavus rather than A. alternata is predominantly isolated from such patients in Asia. We compared immunological response to A. flavus and...