Development of rheumatoid arthritis specific HLA-DRB1 genotyping microarray

• Published in: Biochip journal Vol. 8; no. 3; pp. 187 - 198
• Main Authors: Lee, Seung Yong, Yu, So Yeon, Bang, So-Young, Kim, Ji-Hoon, Kim, Seung Jun, Hong, Sung-Hyun, Kim, Kwangwoo, Lee, Hye-Soon, Bae, Sang-Cheol, Yoon, Young Ho, Hwang, Seung Yong
• Format: Journal Article
• Language: English
• Published: Heidelberg The Korean BioChip Society (KBCS) 01.09.2014; Springer Nature B.V; 한국바이오칩학회
• Subjects: Alleles; Amino acids; Arthritis; Biomedical Engineering and Bioengineering; Biotechnology; Chemistry; Chemistry and Materials Science; Clinical aspects; DNA microarrays; Drb1 protein; Epitopes; Genotypes; Genotyping; Histocompatibility antigen HLA; Hybridization; Original Article; Probes; Rheumatoid arthritis; Tissue typing; 생물공학; Risk allele; 4 digit; Genotyping; Rheumatoid arthritis; HLA-DRB1; Oligonucleotide microarray

HLA-DRB1 is the most important gene for rheumatoid arthritis (RA) susceptibility. The HLADRB1 shared epitope (SE) alleles that share conserved amino acid sequences and non-SE *09:01 allele account for about one-third of the genetic contribution to RA. We aimed to develop RA specific HLA-DRB1 genotyp...