Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages - Belchamber, Kylie B.R.; Singh, Richa; Batista, Craig M.; Whyte, Moira K.; Dockrell, David H.; Kilty, Iain; Robinson, Matthew J.; Wedzicha, Jadwiga A.; Barnes, Peter J.; Donnelly, Louise E. (The European respiratory journal, 2019)
Keywords: Aged; Bacteria; Cell Survival; Female; Haemophilus influenzae; Humans; In Vitro Techniques; Macrophages - immunology; Macrophages - metabolism; Macrophages - pathology; Macrophages, Alveolar - immunology; Macrophages, Alveolar - metabolism; Macrophages, Alveolar - pathology; Male; Membrane Potential, Mitochondrial; Microscopy, Confocal; Middle Aged; Mitochondria - metabolism; Phagocytosis - immunology; Pulmonary Disease, Chronic Obstructive - immunology; Pulmonary Disease, Chronic Obstructive - metabolism; Reactive Oxygen Species - metabolism; Streptococcus pneumoniae