Chemo‐Phototherapy with Carfilzomib‐Encapsulated TiN Nanoshells Suppressing Tumor Growth and Lymphatic Metastasis

• Published in: Small (Weinheim an der Bergstrasse, Germany) Vol. 18; no. 29; pp. e2200522 - n/a
• Main Authors: Wu, Xuan, Wang, Le, Xu, Yan‐Neng, Chen, Jian‐Li, Luo, Kathy Qian, Yuan, Ming‐Heng, Li, Jie, Yuan, Gang, Gu, Ze‐Yun, Jia, Xiao‐Hui, Chen, Xiuping, Zhu, Xiao‐Ming, Jiang, Ruibin
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley Subscription Services, Inc 01.07.2022
• Subjects: Anticancer properties; autophagy; Cancer therapies; carfilzomib; Drug carriers; In vivo methods and tests; Inhibitors; Light therapy; Metastasis; Nanotechnology; Photothermal conversion; photothermal therapy; proteasome inhibitors; Surgery; Therapy; TiN nanoshells; Titanium nitride; Tumors

The design of nanomedicine for cancer therapy, especially the treatment of tumor metastasis has received great attention. Proteasome inhibition is accepted as a new strategy for cancer therapy. Despite being a big breakthrough in multiple myeloma therapy, carfilzomib (CFZ), a second‐in‐class proteas...