Barrett Esophagus and Intestinal Metaplasia of the Gastroesophageal Junction in Children: A Clinicopathologic Study

OBJECTIVES:Barrett esophagus (BE) and intestinal metaplasia of gastroesophageal junction (IMGEJ) are rare in the pediatric population. This multi-institutional retrospective study evaluated the clinicopathologic characteristics and natural history of BE and IMGEJ in children. METHODS:Data from 20 BE...

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Published inJournal of pediatric gastroenterology and nutrition Vol. 70; no. 5; pp. 562 - 567
Main Authors Putra, Juan, Arva, Nicoleta C., Tan, Serena Y., Melin-Aldana, Hector, Bass, Lee M., Mitchell, Paul D., Fox, Victor L., Goldsmith, Jeffrey D.
Format Journal Article
LanguageEnglish
Published United States by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition 01.05.2020
by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology
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Abstract OBJECTIVES:Barrett esophagus (BE) and intestinal metaplasia of gastroesophageal junction (IMGEJ) are rare in the pediatric population. This multi-institutional retrospective study evaluated the clinicopathologic characteristics and natural history of BE and IMGEJ in children. METHODS:Data from 20 BE patients (70% boys, mean age14.9 years) and 17 IMGEJ patients (71% boys, mean age14 years) were retrospectively obtained from chart review. Endoscopic and pathologic findings from index and follow-up endoscopies were analyzed. RESULTS:Most patients (70% BE and 59% IMGEJ) had underlying conditions which put them at risk for gastroesophageal reflux disease. Increased body mass index (BMI) was observed in patients without underlying conditions (BE30.1 ± 9.8; IMGEJ23.9 ± 6.3) compared with those with underlying conditions (BE19.6 ± 7.8; IMGEJ16.4 ± 2.1) (BE, P = 0.02; IMGEJ, P = 0.01). Incomplete intestinal metaplasia (IM) was the predominant histology seen in BE (80%) and IMGEJ patients (75%). Dysplasia and malignancy were not identified in the initial and follow-up biopsies. Concurrent gastric biopsies showed various findings (79% BE and 40% IMGEJ were normal), with 1 IMGEJ patient showing coexisting gastric IM (7%). Follow-up in 12 BE patients (mean follow-up time 51.6 months) showed 100% persistent endoscopic disease and 58% persistent IM histologically. Three of 6 IMGEJ patients (mean follow-up time 24 months) demonstrated endoscopic and histologic features consistent with BE on subsequent procedures. Moreover, a subset of BE (57%) and IMGEJ patients (67%) who underwent endoscopy before initial diagnosis showed nongoblet columnar mucosa above the anatomic gastroesophageal junction. CONCLUSIONS:Increased BMI may be a risk factor for BE and IMGEJ in pediatric patients without underlying conditions. Nongoblet columnar metaplasia and IMGEJ might represent incomplete forms of BE. Our data suggest that these patients should be closely monitored.
AbstractList Barrett esophagus (BE) and intestinal metaplasia of gastroesophageal junction (IMGEJ) are rare in the pediatric population. This multi-institutional retrospective study evaluated the clinicopathologic characteristics and natural history of BE and IMGEJ in children. Data from 20 BE patients (70% boys, mean age: 14.9 years) and 17 IMGEJ patients (71% boys, mean age: 14 years) were retrospectively obtained from chart review. Endoscopic and pathologic findings from index and follow-up endoscopies were analyzed. Most patients (70% BE and 59% IMGEJ) had underlying conditions which put them at risk for gastroesophageal reflux disease. Increased body mass index (BMI) was observed in patients without underlying conditions (BE: 30.1 ± 9.8; IMGEJ: 23.9 ± 6.3) compared with those with underlying conditions (BE: 19.6 ± 7.8; IMGEJ: 16.4 ± 2.1) (BE, P = 0.02; IMGEJ, P = 0.01). Incomplete intestinal metaplasia (IM) was the predominant histology seen in BE (80%) and IMGEJ patients (75%). Dysplasia and malignancy were not identified in the initial and follow-up biopsies. Concurrent gastric biopsies showed various findings (79% BE and 40% IMGEJ were normal), with 1 IMGEJ patient showing coexisting gastric IM (7%). Follow-up in 12 BE patients (mean follow-up time 51.6 months) showed 100% persistent endoscopic disease and 58% persistent IM histologically. Three of 6 IMGEJ patients (mean follow-up time 24 months) demonstrated endoscopic and histologic features consistent with BE on subsequent procedures. Moreover, a subset of BE (57%) and IMGEJ patients (67%) who underwent endoscopy before initial diagnosis showed nongoblet columnar mucosa above the anatomic gastroesophageal junction. Increased BMI may be a risk factor for BE and IMGEJ in pediatric patients without underlying conditions. Nongoblet columnar metaplasia and IMGEJ might represent incomplete forms of BE. Our data suggest that these patients should be closely monitored.
OBJECTIVES:Barrett esophagus (BE) and intestinal metaplasia of gastroesophageal junction (IMGEJ) are rare in the pediatric population. This multi-institutional retrospective study evaluated the clinicopathologic characteristics and natural history of BE and IMGEJ in children. METHODS:Data from 20 BE patients (70% boys, mean age14.9 years) and 17 IMGEJ patients (71% boys, mean age14 years) were retrospectively obtained from chart review. Endoscopic and pathologic findings from index and follow-up endoscopies were analyzed. RESULTS:Most patients (70% BE and 59% IMGEJ) had underlying conditions which put them at risk for gastroesophageal reflux disease. Increased body mass index (BMI) was observed in patients without underlying conditions (BE30.1 ± 9.8; IMGEJ23.9 ± 6.3) compared with those with underlying conditions (BE19.6 ± 7.8; IMGEJ16.4 ± 2.1) (BE, P = 0.02; IMGEJ, P = 0.01). Incomplete intestinal metaplasia (IM) was the predominant histology seen in BE (80%) and IMGEJ patients (75%). Dysplasia and malignancy were not identified in the initial and follow-up biopsies. Concurrent gastric biopsies showed various findings (79% BE and 40% IMGEJ were normal), with 1 IMGEJ patient showing coexisting gastric IM (7%). Follow-up in 12 BE patients (mean follow-up time 51.6 months) showed 100% persistent endoscopic disease and 58% persistent IM histologically. Three of 6 IMGEJ patients (mean follow-up time 24 months) demonstrated endoscopic and histologic features consistent with BE on subsequent procedures. Moreover, a subset of BE (57%) and IMGEJ patients (67%) who underwent endoscopy before initial diagnosis showed nongoblet columnar mucosa above the anatomic gastroesophageal junction. CONCLUSIONS:Increased BMI may be a risk factor for BE and IMGEJ in pediatric patients without underlying conditions. Nongoblet columnar metaplasia and IMGEJ might represent incomplete forms of BE. Our data suggest that these patients should be closely monitored.
OBJECTIVESBarrett esophagus (BE) and intestinal metaplasia of gastroesophageal junction (IMGEJ) are rare in the pediatric population. This multi-institutional retrospective study evaluated the clinicopathologic characteristics and natural history of BE and IMGEJ in children. METHODSData from 20 BE patients (70% boys, mean age: 14.9 years) and 17 IMGEJ patients (71% boys, mean age: 14 years) were retrospectively obtained from chart review. Endoscopic and pathologic findings from index and follow-up endoscopies were analyzed. RESULTSMost patients (70% BE and 59% IMGEJ) had underlying conditions which put them at risk for gastroesophageal reflux disease. Increased body mass index (BMI) was observed in patients without underlying conditions (BE: 30.1 ± 9.8; IMGEJ: 23.9 ± 6.3) compared with those with underlying conditions (BE: 19.6 ± 7.8; IMGEJ: 16.4 ± 2.1) (BE, P = 0.02; IMGEJ, P = 0.01). Incomplete intestinal metaplasia (IM) was the predominant histology seen in BE (80%) and IMGEJ patients (75%). Dysplasia and malignancy were not identified in the initial and follow-up biopsies. Concurrent gastric biopsies showed various findings (79% BE and 40% IMGEJ were normal), with 1 IMGEJ patient showing coexisting gastric IM (7%). Follow-up in 12 BE patients (mean follow-up time 51.6 months) showed 100% persistent endoscopic disease and 58% persistent IM histologically. Three of 6 IMGEJ patients (mean follow-up time 24 months) demonstrated endoscopic and histologic features consistent with BE on subsequent procedures. Moreover, a subset of BE (57%) and IMGEJ patients (67%) who underwent endoscopy before initial diagnosis showed nongoblet columnar mucosa above the anatomic gastroesophageal junction. CONCLUSIONSIncreased BMI may be a risk factor for BE and IMGEJ in pediatric patients without underlying conditions. Nongoblet columnar metaplasia and IMGEJ might represent incomplete forms of BE. Our data suggest that these patients should be closely monitored.
Author Bass, Lee M.
Putra, Juan
Goldsmith, Jeffrey D.
Arva, Nicoleta C.
Fox, Victor L.
Tan, Serena Y.
Melin-Aldana, Hector
Mitchell, Paul D.
AuthorAffiliation Department of Pathology, Children's Hospital Boston and Harvard Medical School, Boston, MA
Department of Pathology and Laboratory Medicine
Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
Institutional Centers for Clinical and Translational Research
Division of Gastroenterology, Hepatology, and Nutrition
Division of Pathology, Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
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Cites_doi 10.1016/j.gie.2006.03.010
10.1097/MPG.0000000000001558
10.1016/j.dld.2011.02.003
10.1007/s10620-008-0413-9
10.1038/ajg.2015.322
10.1038/ajg.2011.130
10.1172/JCI107084
10.1136/gut.45.5.644
10.1111/j.1651-2227.2010.01834.x
10.1186/1750-1172-7-S1-S4
10.1038/ajg.2017.13
10.1038/ajg.2009.728
10.4251/wjgo.v4.i3.30
10.5056/jnm.2013.19.4.538
10.1016/j.gie.2011.01.017
10.1016/j.gtc.2015.02.001
10.1055/s-0033-1347911
10.1111/ped.13114
10.1111/j.1572-0241.2002.05820.x
10.1111/j.1572-0241.2003.08707.x
10.1136/gutjnl-2013-305997
10.1007/s10620-018-5161-x
10.1053/j.gastro.2013.05.040
10.1111/j.1572-0241.2004.40586.x
10.1097/MPG.0b013e3181b7f563
10.3109/17477166.2010.491118
10.1097/MCG.0b013e3181705ce9
10.1002/ddrr.18
10.1097/MPH.0b013e31822814b2
10.5858/arpa.2011-0019-RA
10.1053/j.gastro.2012.08.045
10.1097/00000658-200111000-00006
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2020 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology
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References 32740523 - J Pediatr Gastroenterol Nutr. 2020 Oct;71(4):e136-e137
32740521 - J Pediatr Gastroenterol Nutr. 2020 Oct;71(4):e136
e_1_2_5_26_2
e_1_2_5_27_2
e_1_2_5_24_2
e_1_2_5_25_2
e_1_2_5_22_2
e_1_2_5_23_2
e_1_2_5_20_2
e_1_2_5_21_2
e_1_2_5_29_2
e_1_2_5_14_2
e_1_2_5_13_2
e_1_2_5_9_2
e_1_2_5_16_2
e_1_2_5_35_2
e_1_2_5_8_2
e_1_2_5_15_2
e_1_2_5_36_2
e_1_2_5_7_2
e_1_2_5_33_2
e_1_2_5_6_2
e_1_2_5_34_2
e_1_2_5_5_2
e_1_2_5_12_2
e_1_2_5_31_2
e_1_2_5_4_2
e_1_2_5_11_2
e_1_2_5_32_2
e_1_2_5_2_2
Kuczmarski RJ (e_1_2_5_10_2) 2002; 246
Hassall E (e_1_2_5_3_2) 1993; 88
e_1_2_5_18_2
e_1_2_5_17_2
e_1_2_5_19_2
e_1_2_5_30_2
Chang P (e_1_2_5_28_2) 2014; 43
References_xml – ident: e_1_2_5_4_2
  doi: 10.1016/j.gie.2006.03.010
– ident: e_1_2_5_6_2
  doi: 10.1097/MPG.0000000000001558
– ident: e_1_2_5_7_2
  doi: 10.1016/j.dld.2011.02.003
– ident: e_1_2_5_29_2
  doi: 10.1007/s10620-008-0413-9
– ident: e_1_2_5_2_2
  doi: 10.1038/ajg.2015.322
– ident: e_1_2_5_11_2
  doi: 10.1038/ajg.2011.130
– ident: e_1_2_5_23_2
  doi: 10.1172/JCI107084
– ident: e_1_2_5_32_2
  doi: 10.1136/gut.45.5.644
– ident: e_1_2_5_21_2
  doi: 10.1111/j.1651-2227.2010.01834.x
– volume: 88
  start-page: 819
  year: 1993
  ident: e_1_2_5_3_2
  article-title: Barrett's esophagus: congenital or acquired
  publication-title: Am J Gastroenterol
  contributor:
    fullname: Hassall E
– volume: 246
  start-page: 1
  year: 2002
  ident: e_1_2_5_10_2
  article-title: 2000 CDC Growth Charts for the United States: methods and development
  publication-title: Vital Health Stat 11
  contributor:
    fullname: Kuczmarski RJ
– ident: e_1_2_5_22_2
  doi: 10.1186/1750-1172-7-S1-S4
– ident: e_1_2_5_14_2
  doi: 10.1038/ajg.2017.13
– ident: e_1_2_5_34_2
  doi: 10.1038/ajg.2009.728
– ident: e_1_2_5_33_2
  doi: 10.4251/wjgo.v4.i3.30
– ident: e_1_2_5_20_2
  doi: 10.5056/jnm.2013.19.4.538
– ident: e_1_2_5_15_2
  doi: 10.1016/j.gie.2011.01.017
– ident: e_1_2_5_17_2
  doi: 10.1016/j.gtc.2015.02.001
– ident: e_1_2_5_19_2
  doi: 10.1055/s-0033-1347911
– ident: e_1_2_5_9_2
  doi: 10.1111/ped.13114
– ident: e_1_2_5_16_2
  doi: 10.1111/j.1572-0241.2002.05820.x
– ident: e_1_2_5_24_2
  doi: 10.1111/j.1572-0241.2003.08707.x
– ident: e_1_2_5_13_2
  doi: 10.1136/gutjnl-2013-305997
– ident: e_1_2_5_35_2
  doi: 10.1007/s10620-018-5161-x
– ident: e_1_2_5_36_2
  doi: 10.1053/j.gastro.2013.05.040
– ident: e_1_2_5_30_2
  doi: 10.1111/j.1572-0241.2004.40586.x
– ident: e_1_2_5_18_2
  doi: 10.1097/MPG.0b013e3181b7f563
– volume: 43
  start-page: 161
  year: 2014
  ident: e_1_2_5_28_2
  article-title: Gastroenterol
  publication-title: Clin North Am
  contributor:
    fullname: Chang P
– ident: e_1_2_5_26_2
  doi: 10.3109/17477166.2010.491118
– ident: e_1_2_5_27_2
  doi: 10.1097/MCG.0b013e3181705ce9
– ident: e_1_2_5_5_2
  doi: 10.1002/ddrr.18
– ident: e_1_2_5_8_2
  doi: 10.1097/MPH.0b013e31822814b2
– ident: e_1_2_5_12_2
  doi: 10.5858/arpa.2011-0019-RA
– ident: e_1_2_5_25_2
  doi: 10.1053/j.gastro.2012.08.045
– ident: e_1_2_5_31_2
  doi: 10.1097/00000658-200111000-00006
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Snippet OBJECTIVES:Barrett esophagus (BE) and intestinal metaplasia of gastroesophageal junction (IMGEJ) are rare in the pediatric population. This multi-institutional...
Barrett esophagus (BE) and intestinal metaplasia of gastroesophageal junction (IMGEJ) are rare in the pediatric population. This multi-institutional...
OBJECTIVESBarrett esophagus (BE) and intestinal metaplasia of gastroesophageal junction (IMGEJ) are rare in the pediatric population. This multi-institutional...
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Title Barrett Esophagus and Intestinal Metaplasia of the Gastroesophageal Junction in Children: A Clinicopathologic Study
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https://www.ncbi.nlm.nih.gov/pubmed/31977949
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