Optimal control of a batch fermentation process with nonlinear time-delay and free terminal time and cost sensitivity constraint

• Published in: Journal of process control Vol. 44; pp. 41 - 52
• Main Authors: Yuan, Jinlong, Liu, Chongyang, Zhang, Xu, Xie, Jun, Feng, Enmin, Yin, Hongchao, Xiu, Zhilong
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.08.2016
• Subjects: Batch fermentation; Cost sensitivity constraint; Free terminal time; Nonlinear time-delay system; Optimal control; Parallel optimization; Free terminal time; Cost sensitivity constraint; Parallel optimization; Nonlinear time-delay system; Optimal control; Batch fermentation

•An control problem is proposed to maximize the productivity of 1,3-PD.•The problem with free terminal time is transformed via a hybrid time-scaling strategy.•A parallel algorithm is proposed to solve the problem.•We consider a cost sensitivity constraint to reflect operational requirements. In this...