First-in-Human Serum Stability Studies of [ 177 Lu]Lu-AMTG: A Step Toward Improved GRPR-Targeted Radiopharmaceutical Therapy - Felber, Veronika; Holzleitner, Nadine; Joksch, Markus; Suhrbier, Tim; von Amsberg, Gunhild; Schwarzenböck, Sarah; Kurth, Jens; Heuschkel, Martin; Günther, Thomas; Krause, Bernd J. (Journal of Nuclear Medicine, 2025)
Keywords: Drug Stability; Humans; Lutetium - chemistry; Lutetium - therapeutic use; Male; Molecular Targeted Therapy; Positron Emission Tomography Computed Tomography; Radioisotopes - therapeutic use; Radiopharmaceuticals - blood; Radiopharmaceuticals - chemistry; Radiopharmaceuticals - pharmacokinetics; Radiopharmaceuticals - therapeutic use; Receptors, Bombesin - metabolism; AMTG; first-in-human; GRPR; in vivo serum stability; 177Lu