The TUBEX™ typhoid test based on particle-inhibition immunoassay detects IgM but not IgG anti-O9 antibodies

• Published in: Journal of immunological methods Vol. 282; no. 1; pp. 83 - 91
• Main Authors: Tam, Frankie Chi Hang, Lim, Pak Leong
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.11.2003
• Subjects: Animals; Antibodies, Bacterial - analysis; Diagnosis; Humans; Immunoassay; Immunoassays; Immunoglobulin G - analysis; Immunoglobulin M - analysis; Infection; Mice; O Antigens - immunology; Rapid tests; Reagent Kits, Diagnostic; Salmonella typhi - immunology; Serology; Typhoid Fever - diagnosis; Infection; Rapid tests; Serology; Diagnosis; Immunoassays

A serological test kit (TUBEX™, IDL Biotech, Sweden) developed recently for the diagnosis of typhoid fever detects antibodies to the Salmonella enterica serovar Typhi lipopolysaccharide (LPS) O9 antigen. The antibodies are detected by their ability to inhibit the interaction between two types of rea...