Jak Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition - Groner, Bernd; von Manstein, Viktoria (Molecular and cellular endocrinology, 2017)
Keywords: Antineoplastic Agents - therapeutic use; Cell Proliferation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Immune therapy; Immunotherapy - methods; Jak stat signaling in cancer; Janus Kinases - antagonists & inhibitors; Janus Kinases - genetics; Janus Kinases - immunology; Molecular Targeted Therapy; Neoplasm Invasiveness; Neoplasms - genetics; Neoplasms - immunology; Neoplasms - pathology; Neoplasms - therapy; Neoplastic Stem Cells - drug effects; Neoplastic Stem Cells - immunology; Neoplastic Stem Cells - pathology; Signal Transduction; Signaling pathway interactions; STAT Transcription Factors - antagonists & inhibitors; STAT Transcription Factors - genetics; STAT Transcription Factors - immunology; Targeted therapeutics; Tumor microenvironment; Tumor Microenvironment - drug effects; Immune therapy; Targeted therapeutics; Signaling pathway interactions; Tumor microenvironment; Jak stat signaling in cancer