Design and construction of multi epitope- peptide vaccine candidate for rabies virus

• Published in: Bioinformation Vol. 19; no. 2; pp. 167 - 177
• Main Authors: Abdulhameed Odhar, Hasanain, Hashim, Ahmed Fadhil, Humadi, Suhad Sami, Ahjel, Salam Waheed
• Format: Journal Article
• Language: English
• Published: Singapore Biomedical Informatics 28.02.2023
• Subjects: Antibodies; Antigens; Bats; Encephalitis; Epitope mapping; Glycoproteins; Immune response; Immune system; Informatics; Lymphocytes B; Lymphocytes T; Lyssavirus; Molecular docking; Peptides; Rabies; Vaccines; Viruses; docking; rabies; glycoprotein; dynamics simulation; epitope; peptide vaccine

Rabies virus is a zoonotic pathogen that causes lethal encephalitis with a case fatality rate of almost 100% in unvaccinated individuals. The currently available vaccines against rabies are composed of inactivated viral particles that only confer a short-term immune response. It is well-known that t...