Adrenal androgens and human breast cancer : A new appraisal

• Published in: Breast cancer research and treatment Vol. 51; no. 2; pp. 183 - 188
• Main Author: ADAMS, J. B
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer 01.09.1998; Springer Nature B.V
• Subjects: Adrenal Cortex Hormones - blood; Age Factors; Androgens; Androgens - blood; Biological and medical sciences; Breast cancer; Breast Neoplasms - blood; Breast Neoplasms - etiology; Cancer research; Cell growth; Estradiol - blood; Female; Gynecology. Andrology. Obstetrics; Humans; Mammary gland diseases; Medical sciences; Postmenopause; Risk Factors; Tumors; Human; Androgen; Pathogenesis; Estrogen; Androstenediol; Malignant tumor; Mammary gland diseases; Dehydroepiandrosterone; Dehydroepiandrosterone sulfate; Adrenal hormone; Female; Mammary gland; Androstenedione; Sex steroid hormone; Hormonal receptor

A clearer picture of the role of adrenal androgens in the etiology of breast cancer is beginning to emerge. Women who develop breast cancer in premenopausal years tend to have subnormal serum levels of adrenal androgens, while subjects who develop the disease in postmenopausal years have supranormal...