A Novel Grading Biomarker for the Prediction of Conversion From Mild Cognitive Impairment to Alzheimer's Disease - Tong, Tong; Gao, Qinquan; Guerrero, Ricardo; Ledig, Christian; Chen, Liang; Rueckert, Daniel; Initiative, Alzheimer's Disease Neuroimaging (IEEE transactions on biomedical engineering, 2017)
Keywords: Age; Aged; Aging; Aging - pathology; Algorithms; Alzheimer Disease - diagnostic imaging; Alzheimer Disease - etiology; Alzheimer Disease - pathology; Alzheimer's disease; Alzheimer's disease (AD); biomarker; Biomarkers; Biomedical imaging; Biomedical measurement; Brain - pathology; Classification; Clinical trials; Cognitive ability; Cognitive Dysfunction - complications; Cognitive Dysfunction - diagnostic imaging; Cognitive Dysfunction - pathology; Conversion; Datasets; Disease Progression; Female; Humans; Image Interpretation, Computer-Assisted - methods; Impairment; Integration; machine learning; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Mathematical analysis; Medical imaging; Neurodegenerative diseases; Neuroimaging; Pathology; Pattern Recognition, Automated - methods; prediction of mild cognitive impairment (MCI) conversion; Representations; Reproducibility of Results; Sensitivity and Specificity; structural magnetic resonance (MR) imaging; Subtraction Technique