Gender differences in serum markers of bone resorption in healthy subjects and patients with disorders affecting bone

• Published in: Osteoporosis international Vol. 13; no. 2; pp. 171 - 175
• Main Authors: Minisola, S, Dionisi, S, Pacitti, M T, Paglia, F, Carnevale, V, Scillitani, A, Mazzaferro, S, De, Geronimo S, Pepe, J, Derasmo, E, Romagnoli, E
• Format: Journal Article
• Language: English
• Published: England Springer Nature B.V 01.01.2002
• Subjects: Acid Phosphatase - blood; Adult; Age; Aged; Aged, 80 and over; Aging - blood; Biomarkers - blood; Bone diseases; Bone Diseases - blood; Bone Diseases, Endocrine - blood; Bone Diseases, Metabolic - blood; Bone Resorption - blood; Collagen - blood; Collagen Type I; Female; Fractures; Gender differences; Hibernation; Humans; Isoenzymes - blood; Male; Metabolism; Middle Aged; Osteoporosis; Peptides - blood; Phosphatase; Sex Characteristics; Sexes; Standard scores; Tartrate-Resistant Acid Phosphatase; Womens health

To assess how two different serum markers of bone resorption may reflect changes in bone turnover, we compared age- and sex-related changes in serum C-terminal telopeptide of type I collagen (betaCTx) and tartrate-resistant acid phosphatase activity (TRAP) in 136 healthy men and 184 normal women. Se...