Proteomic analysis of human follicular fluid from polycystic ovary syndrome patients

• Published in: Biotechnology and applied biochemistry Vol. 69; no. 1; p. 289
• Main Authors: Sim, Young-Jin, Ryu, A-Reum, Lee, Mi-Young
• Format: Journal Article
• Language: English
• Published: United States 01.02.2022
• Subjects: Adult; Electrophoresis, Gel, Two-Dimensional; Female; Fertilization in Vitro; Follicular Fluid; Humans; Polycystic Ovary Syndrome; Proteomics; human follicular fluid; proteomics; gelsolin; polycystic ovary syndrome; vitamin D binding protein

Comparative proteomic profiling of human follicular fluid (HFF) from polycystic ovary syndrome (PCOS) and non-PCOS patients who displayed low levels of fertility was carried out via two-dimensional gel electrophoresis (2-DE) combined with mass spectrometry. HFF, an important reproductive fluid, was...